Transition from parenteral to enteral nutrition induces immediate diet - 1 dependent gut histological and immunological responses in preterm neonates
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چکیده
Transition from parenteral to enteral nutrition induces immediate diet1 dependent gut histological and immunological responses in preterm neonates 2 3 Jayda Siggers, Per T. Sangild, Tim K. Jensen, Richard H. Siggers, Kerstin Skovgaard, Ann 4 Cathrine F. Støy, Bent B. Jensen, Thomas Thymann, Stine B. Bering, Mette Boye 5 6 Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen, DK-1958 7 Frederiksberg, Denmark; National Veterinary Institute, Technical University of Denmark, DK8 1790 Copenhagen, Denmark; 3 Department of Animal Health and Bioscience, Aarhus University, 9 DK-8830 Tjele, Denmark 10 11 12 Running head: Temporal development of NEC in preterm neonates 13 14 15 16 17 18 19 Corresponding author: 20 Per T. Sangild, Department of Human Nutrition, 30 Rolighedsvej, DK-1958 Frederiksberg C, 21 Denmark; tel. +45 35 33 26 98; fax +45 35 33 24 69; E-mail [email protected] 22 23 Articles in PresS. Am J Physiol Gastrointest Liver Physiol (June 23, 2011). doi:10.1152/ajpgi.00400.2010
منابع مشابه
Transition from parenteral to enteral nutrition induces immediate diet-dependent gut histological and immunological responses in preterm neonates.
Necrotizing enterocolitis (NEC) in preterm infants develops very rapidly from a mild intolerance to enteral feeding into intestinal mucosal hemorrhage, inflammation, and necrosis. We hypothesized that immediate feeding-induced gut responses precede later clinical NEC symptoms in preterm pigs. Fifty-six preterm pigs were fed total parenteral nutrition (TPN) for 48 h followed by enteral feeding f...
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Preterm neonates have an immature gut and metabolism and may benefit from total parenteral nutrition (TPN) before enteral food is introduced. Conversely, delayed enteral feeding may inhibit gut maturation and sensitize to necrotizing enterocolitis (NEC). Intestinal mass and NEC lesions were first recorded in preterm pigs fed enterally (porcine colostrum, bovine colostrum, or formula for 20-40 h...
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BACKGROUND Small enteral boluses with human milk may reduce the risk of subsequent feeding intolerance and necrotizing enterocolitis in preterm infants receiving parenteral nutrition (PN). We hypothesized that feeding amniotic fluid, the natural enteral diet of the mammalian fetus, will have similar effects and improve growth and gastrointestinal (GI) maturation in preterm neonates receiving PN...
متن کاملTotal parenteral nutrition in infancy: effect on the liver and suggested pathogenesis.
Biochemical, histological, and electron-microscopic investigation of seven preterm infants who became jaundiced after prolonged total parenteral nutrition showed conjugated hyperbilirubinaemia apparently due to cholestasis without significant primary liver cell injury. In the absence of evidence indicating a direct toxic effect on the liver of this form of nutrition the necropsy findings in one...
متن کاملBenefits of probiotics on enteral nutrition in preterm neonates: a systematic review.
INTRODUCTION The optimization of enteral nutrition is a priority in preterm neonates worldwide. Probiotics are known to improve gut maturity and function in preterm neonates. To our knowledge, previous systematic reviews have not adequately assessed the effects of probiotic supplementation on enteral nutrition in preterm neonates. OBJECTIVE We assessed the evidence on effects of probiotics on...
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تاریخ انتشار 2011